"We don't have this under control at the moment".

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Re: "We don't have this under control at the moment".

Postby Suff » 04 Oct 2020, 13:28

This is what the vaccine testers recommend. It has been proven that they need the booster and it is not effective to try and test everyone to see who needs the booster.

As the weeks roll forward we should hear more of their plans. It is prudent to assume there may be 9ne moe holdup for an adverse reaction, but the current end date for the phase 3 2 round tests is mid Oct with the existing week delay.

We will hear more when it ends.
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Re: "We don't have this under control at the moment".

Postby Workingman » 04 Oct 2020, 14:52

I did a quick crunch of the numbers and it shows that with everyone chipping in it is doable over a rolling four week period. First four weeks = initial jab, second four weeks = booster.

Here 500.000 are covered by 147 GP surgeries with an average of four staff able to give intra-muscular injections. There are also a number of community health / drop-in centres with practitioner nurses also able to give injections. And a large number of those receiving injections will be in care homes with HCAs licenced to inject. Then there are the hospitals, St John's ambulance....

Yes, it will be damned hard work, but remember, it is a one-off operation in a pandemic.

BTW that "army" of 30,000 people trained to give intra-muscular injections is no big deal. I was a first-aider in the RAF and that module was done in a few hours. Also in the RAF, on initial training, we were given combined injections. It took less than a morning to do about 500 of us with about 10 medics - form a line, roll up sleeve, swab, jab, hold on swab, exit.
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Re: "We don't have this under control at the moment".

Postby Suff » 04 Oct 2020, 15:09

With perfect execution WM. It is feasible but I don't expect it to go quite as well.

Easter is a worst case end date if all goes well.
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Re: "We don't have this under control at the moment".

Postby Workingman » 04 Oct 2020, 15:33

Easter starts on the 2nd April, so not such a big delay. Urban areas should be fine, it's the rural areas that could face problems, as always. Mind you we could set up something like the mobile Blood Donation units going on tours then starting again after four weeks to give the boosters.

We have got the time to plan and set up. Put the military in charge and do the job properly.
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Re: "We don't have this under control at the moment".

Postby Suff » 05 Oct 2020, 09:50

Workingman wrote:We have got the time to plan and set up. Put the military in charge and do the job properly.


My vote too. But whether they will or not???
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Re: "We don't have this under control at the moment".

Postby cromwell » 05 Oct 2020, 09:59

I don't know if either of you have got this sense, but I'm seeing on social media that lots of people will refuse the vaccine. If lots of people refuse then where does that leave us, compulsory inoculation? Coercion?
I don't think it's just going to be a question of everybody turning up for their jab.
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Re: "We don't have this under control at the moment".

Postby Suff » 05 Oct 2020, 10:09

No I think it will be a divide. Get the vaccine, be free to move and work. Don't get the vaccine, be free to live and work at home.

I'm sure there will be all sorts of "coercion" rolled out when the time comes. Like the trumpeting of the success of vaccines and the deaths that happened before them. Polio, Smallpox, TB, etc.

There is an essential conflict which needs to be resolved. In normal times a vaccine will be followed up, people will be expected to "catch" the disease and be protected, long term studies show the effectiveness of the vaccine so that they can be sure of whether they need to vaccinate yearly or not, etc. Because of this level of caution, there is a strong push to "make sure" before vaccinating.

The only problem with that is 1m people dead and a constantly growing dead pile. Emergency use will be authorised. Because of the emergency use, the stats on effectiveness, who is likely to have a violent reaction (after all some people die from eating one peanut), and just how long it will last, will happen much faster.

One year from now, most of this debate will be gone. Those who refuse the vaccine may find themselves facing restrictions, loss of job, career, home etc. Stark choice.
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Re: "We don't have this under control at the moment".

Postby cromwell » 05 Oct 2020, 10:27

Suff wrote:One year from now, most of this debate will be gone. Those who refuse the vaccine may find themselves facing restrictions, loss of job, career, home etc. Stark choice.


It is and it will be interesting to see how the nation reacts to that choice. We are not a dictatorship and if the government tries to force their wishes on the population they may be surprised at how many people refuse to conform.
And as we have become a very litigious nation, like the states, I would expect any compulsion or coercion to be challenged in the courts.
Two volounteers in the Astra Zeneca covid vaccine trial have developed symptoms of transverse myelitis, an auto immune inflammatory condition of the spine. In the general population there are between 1 and 8 cases per million of transverse myelitis.
In the Astra Zeneca trial there have been two cases in less than a thousand people.
If that news ever sinks in lots of people will say "No ta" to the vaccine, because that is seriously worrying news.
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Re: "We don't have this under control at the moment".

Postby Workingman » 05 Oct 2020, 11:56

Kate Bingham, the head of the country's vaccine taskforce, says that initially the over 50s will be the target for the vaccine - about 30 million of us. That tells me that for some time there will be "haves" and "have nots" regardless of the anti-vaxers. How that is going to work to protect us all is beyond me.

I could live with a few refuseniks who would be "known" and could be monitored, but half of us?
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Re: "We don't have this under control at the moment".

Postby Suff » 05 Oct 2020, 12:59

cromwell wrote:Two volounteers in the Astra Zeneca covid vaccine trial have developed symptoms of transverse myelitis, an auto immune inflammatory condition of the spine. In the general population there are between 1 and 8 cases per million of transverse myelitis.
In the Astra Zeneca trial there have been two cases in less than a thousand people.


Oxford University last month announced the start of a Phase II/III UK trial of AZD1222 in about 10,000 adult volunteers. Other late-stage trials are due to begin in a number of countries. AstraZeneca recognises that the vaccine may not work but is committed to progressing the clinical programme with speed and scaling up manufacturing at risk.


30,000 was the target in the US. 2,000 in South Africa for Phase 2, can't find the number for Phase 3. 5,000 in Brazil. India is 1,600.

Astrazeneca is conducting trials of the vaccine, code-named AZD1222, in the UK, Brazil, South Africa and the US, and also plans to start trials in Japan and Russia. These trials will enrol up to 50,000 participants globally, the company had said in a statement on 31 August.


I know it is hard to get good data, but the press repeating Phase 1/2 take up and then allocated 10,000 person issues is doing nobody any good.

With a bit of digging.

Abstract
H1N1 vaccination is currently safe, and only rare acceptable side-effects have been reported. Here we describe for the first time a serious adverse event, i.e., acute transverse myelitis, following H1N1 vaccination in China. After the standard treatment with methylprednislone, the patient recovered completely.

Keywords: H1N1, influenza, vaccination, side-effects, transverse myelitis


Note the date on the publication. Published online 2011 Mar 22.

It is hardly unknown and responds to treatment.

Further down the article.

We thought it worthwhile to present this case and raise the concern to the potential severe adverse events although it is very difficult to confirm or exclude the possible relevance between the vaccination and occurrence of the myelitis since idiopathic myelitis and a number of other common diseases of children may occur coincidentally after vaccinations.
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